Exhibit 99.1

Genworth Financial Announces Fourth Quarter 2010 Results

Strengthens U.S. Mortgage Insurance Reserves By $350 Million

To Address Current Housing Market Expectations

14%¹ Increase in International Net Operating Income

7% Increase in Retirement & Protection Net Operating Income

Richmond, VA (February 2, 2011) – Genworth Financial, Inc. (NYSE: GNW) today reported results for the fourth quarter of 2010. The company reported a net loss² of $161 million, or $0.33 per diluted share, compared with net income of $40 million, or $0.08 per diluted share, in the fourth quarter of 2009. The net operating loss³ for the fourth quarter of 2010 was $135 million, or $0.28 per diluted share, compared with net operating income of $94 million, or $0.19 per diluted share, in the fourth quarter of 2009. Fourth quarter results included approximately $350 million pre-tax of reserve strengthening ($228 million net of tax) in the U.S. Mortgage Insurance (U.S. MI) business, reflecting Genworth’s experience and current expectations of housing market conditions.

At the segment level, Genworth’s results in the quarter included net operating income of $138 million from Retirement and Protection and $117 million in International. This was more than offset by a net operating loss of $352 million in U.S. MI.

“We demonstrated solid International results, improvements in Retirement and Protection and good sales momentum in the fourth quarter,” said Michael D. Fraizer, chairman and chief executive officer. “However, as a result of losses in the U.S. Mortgage Insurance business, our overall results for the quarter and the year were not acceptable. We are taking aggressive actions on several fronts to improve performance in 2011 and beyond, including strengthening U.S. Mortgage Insurance reserves while maintaining good capital flexibility to support new business growth. We are intensely focused on restoring under-performing business lines to acceptable return levels for the capital allocated while sustaining good performance in our other business lines.”

Fourth Quarter Developments & Highlights

Sales and Earnings Growth

U.S MI Loss Trends

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Business Mix

Capital & Investments

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Segment Results

Net operating income (loss) presented in the tables below excludes net investment gains (losses) and other adjustments, net of taxes. In the discussion of International results, all references to percentage changes exclude the impact of foreign exchange. The percentage changes, including the impact of foreign exchange, are included in a table at the end of this press release. The impact of foreign exchange on results in the fourth quarter of 2010 was a favorable $2 million versus the prior year quarter.

A reconciliation of net operating income (loss) of segments and Corporate and Other activities to net income (loss) is included at the end of this press release.

Retirement and Protection

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Retirement and Protection earnings increased seven percent to $138 million compared with $129 million a year ago. Consolidated U.S. life companies ended the quarter with a RBC ratio of approximately 390 percent⁴.

Life insurance earnings were $42 million compared with $43 million in the prior year from higher investment income, which was offset by continued lower persistency on blocks outside the level premium period. Total life sales increased 35 percent from the prior year reflecting a 30 percent increase in traditional universal life sales, and Colony^SM TermUL product grew 41 percent versus traditional term and Colony^SM TermUL products sold a year ago. Average face amount on new business increased by 16 percent to over $350,000 reflecting progress in penetrating the mass affluent market.

LTC earnings decreased $6 million to $43 million reflecting higher claims experience on older blocks, partially offset by improved investment yields and new business profitability. Results in the quarter included an approximately $13 million reserve increase associated with an annual review of claims duration and a $17 million favorable adjustment to defer costs associated with the sale of policies that were incorrectly expensed as a result of a system conversion in late 2008. Individual LTC sales increased $9 million year over year, mainly from growth in the independent channel.

Wealth management earnings increased to $11 million reflecting revenue growth associated with steadily increasing average AUM and lower taxes, partially offset by planned expense increases associated with new business growth initiatives. The business experienced positive net flows in the quarter of $646 million.

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Retirement income fee-based earnings were $21 million, up from $18 million in the prior year quarter, primarily from $3 million favorable tax items. Total variable annuity sales were $254 million compared with $204 million in the prior year quarter. In January 2011, the company announced that it will discontinue sales of group and individual variable annuities.

Retirement income spread-based earnings increased to $21 million, compared with $12 million in the prior year quarter, from improved investment performance from lower cash balances, favorable mortality and lower lapse rates. Total spread-based AUM decreased to $18.5 billion.

International

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International earnings increased 14 percent¹ to $117 million primarily driven by improved earnings in Canada and Australia.

In Canada, national home prices remained flat over 2009 levels while on a sequential basis home prices increased modestly. The quarter end unemployment rate improved sequentially to 7.6 percent from 8.0 percent.

Canadian operating earnings increased 19 percent¹ from the prior year primarily from lower losses and higher revenues, partially offset by higher debt and volume related expenses. The loss ratio declined to 32 percent in the fourth quarter from 39 percent in the prior year with lower severity reflecting improved economic conditions.

Flow NIW in Canada increased 15 percent¹ from the prior year quarter from an estimated increase in share and growth in the mortgage origination market as employment trends and improved consumer confidence contributed to higher mortgage volumes.

The regulatory capital ratio in Canada increased sequentially to 156 percent⁴ from 153 percent, well in excess of requirements. GAAP book value for the Canada MI business was $2.6 billion at quarter end, of which $1.5 billion represented Genworth’s 57.5 percent ownership interest.

In Australia, increases in national home prices are estimated to have flattened sequentially and increased modestly over 2009 levels. The quarter end unemployment rate improved sequentially to 5.0 percent from 5.1 percent.

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Australia operating earnings increased 16 percent¹ from the prior year as improved loss experience and lower taxes were partially offset by increased use of reinsurance. The loss ratio decreased to 37 percent, a reduction of eight points compared to a year ago and one point sequentially, reflecting improved economic conditions and ongoing loss mitigation benefits. Flow NIW decreased 36 percent¹ compared to the prior year primarily reflecting a smaller originations market. The recent flooding in Australia affected areas where the company has approximately four percent of its risk in force (RIF). While it is currently unclear how many policies are affected by the flooding, mortgage insurance policies do not cover physical damage, including flooding. Based on available information to date, these conditions are not expected to have a material impact on the company’s financial results. The company will continue to work with its distribution partners and borrowers to handle any developments appropriately.

The regulatory capital ratio in Australia was 153 percent⁴, well in excess of requirements. GAAP book value for Australia mortgage insurance at quarter end was $1.9 billion.

Lifestyle protection earnings were $19 million, compared to $23 million in the prior year period. Results in the prior year included a $6 million benefit related to lower taxes. Current quarter earnings reflected a 21 percent decline in new claim registrations and ongoing benefits from product re-pricing and distributor contract restructuring, partially offset by lower business volumes and higher expenses associated with enhancing distribution capabilities. Sales decreased by three percent¹, reflecting low levels of consumer lending in Europe. Lifestyle protection loss ratio improved to 16 percent in the fourth quarter from 26 percent in the prior year from several pricing actions and improved claims levels. The regulatory capital ratio ended the quarter at 249 percent⁴, well in excess of requirements.

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U.S. Mortgage Insurance

U.S. MI had a $352 million net operating loss reflecting approximately $350 million pre-tax of reserve strengthening, higher paid claims, a decline in loan modifications and continued aging trends in the delinquency inventory, which more than offset a decline in new delinquencies. Paid claims totaled $268 million. The reserve strengthening included approximately $150 million associated with lower cure rates and lower modification benefits in the current period and approximately $200 million reflecting anticipated declines in cure rates going forward. As a result of this reserve strengthening, year end reserves covered approximately 70% of RIF in foreclosure.

Genworth continued to execute its capital flexibility strategy, making good progress on multiple fronts to support new business and overall financial strength.

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Total flow delinquencies declined three percent sequentially in the fourth quarter, reflecting lower new delinquencies and higher paid claims. New flow delinquencies also decreased five percent sequentially, diverging from the normal seasonal pattern of increased delinquencies. At the same time, the inventory of delinquent loans continued to shift to later stage delinquencies with delinquencies that have missed 12 payments or more representing 38 percent of inventory, up from 35 percent in the third quarter. Including the fourth quarter reserve strengthening, the flow average reserve per delinquency increased to $24,300 from $20,400 on a sequential basis.

Loss mitigation activities, including workouts, presales, policy rescissions and targeted settlements, net of reinstatements, resulted in $126 million of savings in the quarter, a decline from the third quarter as loan modifications have slowed. Based upon reporting from the GSEs and certain servicers, 2,439 loans with Genworth mortgage insurance coverage were modified through the Home Affordable Modification Program (HAMP) and 5,439 were modified through other programs, compared to 3,312 and 6,035, respectively, in the third quarter of 2010. Full year loss mitigation savings were $734 million.

Flow NIW increased sequentially by eight percent as the mortgage insurance market size increased modestly. The company’s market share is estimated to be 15 percent. In addition, the Home Affordable Refinance Program (HARP) accounted for about $1.0 billion of insurance that is treated as a modification of the coverage on existing insurance in force rather than NIW.

Gross bulk losses were $14 million. Genworth’s bulk RIF declined to $539 million compared with $771 million in the year ago quarter.

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Corporate and Other

Corporate and Other net operating loss was $38 million compared with $62 million in the prior year quarter. Results in the current year reflect lower taxes and improved investment income from fixed maturity redemptions and limited partnership distributions of approximately $7 million.

Investments

The core yield remained stable at 4.7 percent despite declining interest rates. In addition, during the quarter, the company entered into $1.7 billion of interest rate hedging transactions for the benefit of its LTC business. The company entered into an additional $1.0 billion of similar transactions in January 2011.

Net loss in the quarter included $26 million of net investment losses, net of tax and other adjustments. Excluding $2 million of mark to market valuation gains from securitization entities, after tax net investment losses were $28 million, which included $24 million net of other-than-temporary impairments.

Net unrealized investment losses were $100 million, net of tax and other items, as of December 31, 2010, compared with $1,398 million as of December 31, 2009. The fixed maturity securities portfolio had gross unrealized investment gains of $2.2 billion compared with $1.3 billion as of December 31, 2009 and gross unrealized investment losses of $1.7 billion compared with $3.5 billion as of December 31, 2009.

Stockholders’ Equity

Stockholders’ equity as of December 31, 2010 increased to $13.9 billion, or $28.31 per share, compared with $12.3 billion, or $25.12 per share, as of December 31, 2009. Stockholders’ equity, excluding accumulated other comprehensive income (loss), as of December 31, 2010 was $12.4 billion, or $25.26 per share, compared with $12.4 billion, or $25.46 per share, as of December 31, 2009.

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About Genworth Financial

Genworth Financial, Inc. (NYSE:GNW) is a leading Fortune 500 global financial security company. Genworth has more than $100 billion in assets and employs approximately 6,500 people with a presence in more than 25 countries. Its products and services help meet the investment, protection, retirement and lifestyle needs of more than 15 million customers. Genworth operates through three segments: Retirement and Protection, U.S. Mortgage Insurance and International. Its products and services are offered through financial intermediaries, advisors, independent distributors and sales specialists. Genworth Financial, which traces its roots back to 1871, became a public company in 2004 and is headquartered in Richmond, Virginia. For more information, visit Genworth.com. From time to time Genworth releases important information via postings on its corporate website. Accordingly, investors and other interested parties are encouraged to enroll to receive automatic email alerts and Really Simple Syndication (RSS) feeds regarding new postings. Enrollment information is found under the “Investors” section of Genworth.com.

Conference Call and Financial Supplement Information

This press release and the fourth quarter 2010 financial supplement are now posted on the company’s website. The slide presentation to be used during the conference call will be available on the company’s website during the call. Investors are encouraged to review these materials.

Genworth will conduct a conference call on February 2, 2011 at 9 a.m. (ET) to discuss the quarter’s results and the strategic update for the company. The conference call will be accessible via telephone and the Internet. The dial-in number for Genworth’s February 2, 2011 conference call is 888 401.4675 or 719 325.2277 (outside the U.S.). To participate in the call by webcast, register at http://investor.genworth.com at least 15 minutes prior to the webcast to download and install any necessary software.

The webcast will be archived on the company’s website and a replay of the call will be available at 888 203.1112 or 719 457.0820 (outside the U.S.); passcode 2189430, through February 15, 2011.

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Use of Non-GAAP Measures

This press release includes the non-GAAP financial measure entitled “net operating income (loss).” The chief operating decision maker evaluates segment performance and allocates resources on the basis of net operating income (loss). The company defines net operating income (loss) as income (loss) from continuing operations excluding net income attributable to noncontrolling interests, after-tax net investment gains (losses) and other adjustments and infrequent or unusual non-operating items. This metric excludes these items because the company does not consider them to be related to the operating performance of its segments and Corporate and Other activities. A significant component of the net investment gains (losses) is the result of impairments, the size and timing of which can vary significantly depending on market credit cycles. In addition, the size and timing of other investment gains (losses) are often subject to Genworth’s discretion and are influenced by market opportunities, as well as asset-liability matching considerations. Infrequent or unusual non-operating items are also excluded from net operating income (loss) if, in the company’s opinion, they are not indicative of overall operating trends. While some of these items may be significant components of net income (loss) in accordance with GAAP, the company believes that net operating income (loss), and measures that are derived from or incorporate net operating income (loss), are appropriate measures that are useful to investors because they identify the income (loss) attributable to the ongoing operations of the business. However, net operating income (loss) is not a substitute for GAAP net income (loss). In addition, the company’s definition of net operating income (loss) may differ from the definitions used by other companies. There were no infrequent or unusual non-operating items excluded from net operating income (loss) during the periods presented in this press release other than a $106 million tax benefit related to separation from the company’s former parent recorded in the first quarter of 2010. The tables at the end of this press release reflect net operating income (loss) as determined in accordance with accounting guidance related to segment reporting, and a reconciliation of net operating income (loss) of the company’s segments and Corporate and Other activities to net income (loss) for the three and twelve months ended December 31, 2010 and 2009.

This press release includes the non-GAAP financial measure entitled “core yield” as a measure of investment yield. The company defines core yield as the investment yield adjusted for those items that are not recurring in nature. Management believes that analysis of core yield enhances understanding of the investment yield of the company. However,

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core yield as defined by the company should not be viewed as a substitute for GAAP investment yield. In addition, the company’s definition of core yield may differ from the definitions used by other companies. A reconciliation of core yield to reported GAAP yield is included in a table at the end of this press release.

Definition of Selected Operating Performance Measures

The company reports selected operating performance measures including “sales,” “assets under management” and “insurance in force” or “risk in force” which are commonly used in the insurance and investment industries as measures of operating performance. Management regularly monitors and reports the sales metric as a measure of volume of new and renewal business generated in a period. “Sales” refer to: (1) annualized first-year premiums for term life, long term care and Medicare supplement insurance; (2) new and additional premiums/deposits for universal life insurance, linked-benefits, spread-based and variable products; (3) gross and net flows, which represent gross flows less redemptions, for the wealth management business; (4) written premiums and deposits, gross of ceded reinsurance and cancellations, and premium equivalents, where the company earns a fee for administrative services only business, for lifestyle protection insurance; (5) new insurance written for mortgage insurance, which in each case reflects the amount of business the company generated during each period presented; and (6) written premiums, net of cancellations, for the Mexican insurance operations. Sales do not include renewal premiums on policies or contracts written during prior periods. The company considers annualized first-year premiums, new premiums/deposits, gross and net flows, written premiums, premium equivalents and new insurance written to be measures of the company’s operating performance because they represent a measure of new sales of insurance policies or contracts during a specified period, rather than measures of the company’s revenues or profitability during that period.

Management regularly monitors and reports assets under management for the wealth management business, insurance in force and risk in force. Assets under management for the wealth management business represent third-party assets under management that are not consolidated in the financial statements. Insurance in force for the life, international mortgage and U.S. mortgage insurance businesses is a measure of the aggregate face value of outstanding insurance policies as of the respective reporting date. Risk in force for the international and U.S. mortgage insurance businesses is a measure that recognizes that

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the loss on any particular mortgage loan will be reduced by the net proceeds received upon sale of the underlying property. The company considers assets under management for its wealth management business, insurance in force and risk in force to be measures of the company’s operating performance because they represent measures of the size of the business at a specific date, rather than measures of the company’s revenues or profitability during that period.

This press release also includes a metric related to loss mitigation activities for the U.S. mortgage insurance business. The company defines loss mitigation activities as rescissions, cancellations, borrower loan modifications, repayment plans, lender- and borrower-titled presales and other loan workouts and claim mitigation actions. Estimated savings related to rescissions are the reduction in carried loss reserves, net of premium refunds and reinstatement of prior rescissions. Estimated savings related to loan modifications and other cure related loss mitigation actions represent the reduction in carried loss reserves. For non-cure related actions, including presales, the estimated savings represent the difference between the full claim obligation and the actual amount paid. The company believes that this metric helps to enhance the understanding of the operating performance of the U.S. mortgage insurance business.

These operating measures enable the company to compare its operating performance across periods without regard to revenues or profitability related to policies or contracts sold in prior periods or from investments or other sources.

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Cautionary Note Regarding Forward-Looking Statements

This press release contains certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by words such as “expects,” “intends,” “anticipates,” “plans,” “believes,” “seeks,” “estimates,” “will” or words of similar meaning and include, but are not limited to, statements regarding the outlook for the company’s future business and financial performance. Forward-looking statements are based on management’s current expectations and assumptions, which are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict. Actual outcomes and results may differ materially due to global political, economic, business, competitive, market, regulatory and other factors and risks, including the following:

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The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise.

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Contact Information:

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Condensed Consolidated Statements of Income

(Amounts in millions, except per share amounts)

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Reconciliation of Net Operating Income (Loss) to Net Income (Loss)

(Amounts in millions, except per share amounts)

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Condensed Consolidated Balance Sheets

(Amounts in millions)

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Impact of Foreign Exchange on Operating Results⁶

Three months ended December 31, 2010

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Reconciliation of Core Yield to Reported Yield

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